FIG. 1.

The work flow chart of the patient numbers and their respective groups. FF consisted of patients who were on NNRTI-based combination therapy, SF had PI-based combination, RF had RAL backbone and N had not been exposed to ART. INSTI, integrase strand transfer inhibitor; RT, reverse transcriptase; PR, protease; INT, integrase; NNRTI, nonnucleoside reverse transcriptase inhibitor; FF, first-line failures; SF, second-line failures; PI, protease inhibitor; RAL, raltegravir; RF, antiretroviral failures; ART, antiretroviral therapy.