. Author manuscript; available in PMC: 2019 Jan 9.

Published in final edited form as: Biochemistry. 2017 Oct 31;57(1):117–135. doi: 10.1021/acs.biochem.7b00838

Table 2.

Apparent inactivation parameters for TβL, MetSox, and Glufos against E. coli, S. aureus, and human GS.

GS	TβL			MetSox			Glufos
GS	K_I (μM)	k_inact (min⁻¹)	k_inact/K_I (min⁻¹μM⁻¹ ×10³)	K_I (μM)	k_inact (min⁻¹)	k_inact/K_I (min⁻¹μM⁻¹ ×10³)	K_I (μM)	k_inact (min⁻¹)	k_inact/K_I (min⁻¹μM⁻¹ ×10³)
EC	1.7 ± 0.4^a	0.3 ± 0.1	180 ± 70	3.9 ± 1.1	0.4 ± 0.1	100 ± 40	1.0 ± 0.2	0.7 ± 0.1	700 ± 200
SA	50 ± 10	0.4 ± 0.1	8 ± 3	13 ± 3	0.4 ± 0.1	28 ± 9	13 ± 3	0.4 ± 0.1	30 ± 10
H	130 ± 40	0.3 ± 0.1	2 ± 1	1000 ± 500	0.4 ± 0.2	0.4 ± 0.3	150 ± 60	0.9 ± 0.3	6 ± 3

All standard deviations were determined for three independent trials.