Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 1;11:169–178. doi: 10.2147/JIR.S160573

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Menk et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Protein expression of (A) TNF-α and (B) IL-1β in lungs of rats with mechanical ventilation only (control; n=9), repeated pulmonary lavage and mechanical ventilation (LAV; n=9), and repeated pulmonary lavage, mechanical ventilation, and direct stimulation of the AT2 receptor with C21 (0.03 mg/kg body weight; LAV+C21; n=9).

Notes: Lungs were harvested after 240 min of mechanical ventilation, and protein levels were analyzed using CBA and FACS analysis. Results are given as pg (of the respective cytokine) per mg protein of lung tissue. Data are presented as mean±SEM, Mann–Whitney U-test, *p<0.05 compared with LAV group (n=9).

Abbreviations: AT2, angiotensin II type 2; C21, Compound 21; CBA, cytometric bead array; FACS, fluorescence-activated cell sorting; SEM, standard error of the mean; TNF-α, tumor necrosis factor-alpha.