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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Trends Cancer. 2018 Mar 30;4(5):349–358. doi: 10.1016/j.trecan.2018.03.002

Figure 1. Functional cancer genomics with in vivo CRISPR screening.

Figure 1

In vivo CRISPR screening is a powerful, flexible tool to dissect important processes in cancer. Genome-wide CRISPR screens have illuminated novel regulators of metastasis, malignant transformation, immune evasion, and drug resistance. Moving forward, in vivo CRISPR screens may improve our understanding of other processes, such as angiogenesis, genome instability, and metabolic programming.