Table 3.
Subgroup analysis of correlation between polymorphisms and countries
| miRNA SNP | Country | Comparison | χ2 | Phetero | I2 (%) | P-value | OR | 95% CI |
|---|---|---|---|---|---|---|---|---|
| 196a2 rs11614913 | Chinese | CC vs TT | 6.01 | 0.11 | 50 | 0.08 | 1.30 | 0.97–1.75 |
| CT vs TT | 8.98 | 0.03 | 67 | 0.09 | 1.30 | 0.96–1.75 | ||
| Korean | CC vs TT | 0.15 | 0.70 | 0 | 0.02 | 1.33 | 1.05–1.69 | |
| CT vs TT | 2.08 | 0.15 | 52 | 0.06 | 1.33 | 0.99–1.80 | ||
| Italian | CC vs TT | – | – | – | 0.15 | 0.50 | 0.20–1.29 | |
| CT vs TT | – | – | – | 0.51 | 0.74 | 0.30–1.84 | ||
| 146a rs2910164 | Chinese | CC vs GG | 2.63 | 0.45 | 0 | 0.003 | 1.30 | 1.10–1.54 |
| CG vs GG | 0.66 | 0.88 | 0 | 0.30 | 1.08 | 0.93–1.24 | ||
| Korean | CC vs GG | – | – | – | 0.03 | 1.29 | 1.02–1.63 | |
| CG vs GG | – | – | – | 0.91 | 1.01 | 0.81–1.26 | ||
| Italian | CC vs GG | – | – | – | 0.53 | 1.36 | 0.52–3.53 | |
| CG vs GG | – | – | – | 0.04 | 1.77 | 1.02–3.08 |
Note: Bold values are statistically significant.
Abbreviations: miRNA, microRNA; SNP, single-nucleotide polymorphism; OR, odds ratio; CI, confidence interval.