Table 2.
List of the compounds displaying inhibition of Mycobacterium tuberculosis growth
| SN | Compound | MIC90 (μg/mL) exhibited by compounds for M. tuberculosis growth inhibition | MIC90 (μM) exhibited by compounds for M. tuberculosis growth inhibition | IC50 (μg/mL) exhibited by compounds in biochemical assay |
|---|---|---|---|---|
| 1 | A6 | 10 | 30.67 | ND |
| 2 | A35 | 80 | 211.427 | 33.36 |
| 3 | A36 | 83% inhibition at 200 μg/mL | 551.92 | 10.48 |
| 4 | A65 | 20 | 58.41 | 39.17 |
| 5 | A66 | 5 | 14.2 | ND |
| 6 | A70 | 160 | 441.39 | 68.69 |
| 7 | X6 | 20 | 54.94 | ND |
| 8 | X21 | 2.5 | 7.86 | ND |
| 9 | X44 | 20 | 57.8 | ND |
| 10 | X50 | 10 | 23.41 | ND |
| 11 | X58 | 5 | 14.7 | ND |
| 12 | X67 | 20 | 49.87 | ND |
Note: Compounds were evaluated for their ability to inhibit growth of M. tuberculosis H37Rv by employing REMA assay.
Abbreviations: SN, serial number; ND, not determined; M. tuberculosis, Mycobacterium tuberculosis; REMA, Resazurin Microtiter Assay.