Table 2. A selection of genes newly associated with hair color.

The selection was based on the strength of their effect, which is defined as the standardized linear regression coefficient. Results are given for the UK Biobank, 23andMe, their meta-analysis as well as the meta-analysis results from the VisiGen Consortium. These results were generated linear models and effect sizes (Beta) are given in SD units. The A, C, T and G under the “Reference Allele field” denote the nucleotide of the allele for which the effect size and allele frequencies are reported. Frequencies are given for the reference allele and are the average of observed frequencies in the 23andMe and UK Biobank. Associations with p-values of less than 10-100 are reported as “p<10^-100”.

						UK Biobank				23andMe				Meta-analysis
Chr	Pos(Build37)	SNP ID	Ref. Allele	Freq.	Nearest Gene	N	Beta	SE	p-value	N	Beta	SE	p-value	Beta	SE	p-value
1	8207579	rs80293268	G	0.047	SLC45A1	132221	0.194	0.009	1.54E-97	157651	0.157	0.009	1.29E-67	0.175	0.007	<E-100
1	205181062	rs2369633	T	0.089	DSTYK	132887	-0.071	0.007	9.20E-26	157651	-0.077	0.006	3.15E-38	-0.075	0.005	3.44E-62
2	28613302	rs71443018	G	0.039	FOSL2	126428	0.133	0.01	2.14E-39	157651	0.148	0.012	4.18E-33	0.139	0.008	1.36E-70
9	126808006	rs58979150	T	0.108	LHX2	132883	0.089	0.006	1.03E-44	157651	0.083	0.005	9.93E-53	0.086	0.004	1.40E-95
13	78391757	rs1279403	T	0.406	EDNRB	133238	-0.086	0.004	<E-100	157651	-0.074	0.004	4.57E-95	-0.08	0.003	<E-100
15	48426484	rs1426654	G	0.021	SHC4	133238	0.188	0.069	0.006	157651	0.289	0.03	2.12E-21	0.273	0.028	1.24E-22
17	39551099	rs117612447	T	0.029	KRT31	133238	0.063	0.011	2.95E-08	157651	0.064	0.011	2.09E-09	0.063	0.008	3.29E-16
20	52661068	rs73132911	T	0.046	BCAS1	132836	0.089	0.009	6.78E-22	157651	0.046	0.008	2.54E-09	0.064	0.006	5.85E-27