Table 4.
Estimated annual influenza-associated respiratory deaths and mortality rate per 100 000 population by age group, WHO region, and World Bank income classification
| Age <65 years | Age 65–74 years | Age ≥75 years | All ages | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
|||||||||
| Median annual influenza- associated respiratory mortality* (95% CrI) |
Annual influenza- associated respiratory mortality 95% CrI, per 100 000 individuals* |
Proportion of total influenza- associated respiratory deaths† |
Median annual influenza- associated respiratory mortality* (95% CrI) |
Annual influenza- associated respiratory mortality 95% CrI, per 100 000 individuals* |
Proportion of total influenza- associated respiratory deaths† |
Median annual influenza- associated respiratory mortality* (95% CrI) |
Annual influenza- associated respiratory mortality 95% CrI, per 100 000 individuals* |
Proportion of total influenza- associated respiratory deaths† |
Median annual influenza- associated respiratory mortality* (95% CrI) |
Annual influenza- associated respiratory mortality 95% CrI, per 100 000 individuals* |
Proportion of total influenza- associated respiratory deaths† |
|
| Worldwide | 175 303 | 1·0–5·1 | 42% | 72 720 | 13·3–27·8 | 17% | 172 420 | 51·3–99·4 | 41% | 409 111 | 4·0–8·8 | .. |
| (67 255–342 576) | ( 48 810–102 187) | (122 876–237 933) | (291 243–645 832) | |||||||||
| WHO Regions | ||||||||||||
| Sub-Saharan Africa | 51 767 | 1·0–13·3 | 29% | 8841 | 12·0–80·4 | 13% | 11 874 | 36·3–286·9 | 7% | 69 359 | 2·8–16·5 | 17% |
| (9607–127 569) | (2648–17 744) | (3477–27 502) | (27 813–163 074) | |||||||||
| The Americas | 12 778 | 0·8–2·3 | 8% | 9160 | 10·5–21·5 | 13% | 29 908 | 52·2–105·7 | 17% | 51 674 | 4·2–7·3 | 12% |
| (7027–20 203) | (6236–12 776) | (21 624–43 777) | (41 007–71 710) | |||||||||
| Europe | 10 476 | 0·5–2·5 | 6% | 6566 | 5·0–17·2 | 9% | 27 509 | 23·4–70·7 | 16% | 44 774 | 3·1–8·0 | 11% |
| (4179–19 518) | (3732–12 753) | (15 679–47 438) | (28 457–72 627) | |||||||||
| Eastern Mediterranean | 23 648 | 0·7–11·6 | 13% | 4753 | 7·4–54·1 | 7% | 5777 | 21·8–129·9 | 3% | 33 528 | 2·1–13·4 | 8% |
| (4468–71 208) | (1349–9905) | (2035–12 114) | (13 350–86 490) | |||||||||
| Southeast Asia | 51 412 | 1·2–6·6 | 32% | 21 782 | 14·2–47·5 | 30% | 30 936 | 44·6–130·5 | 18% | 105 167 | 3·5–9·2 | 25% |
| (21 044–119 561) | (10 499–35 014) | (16 602–48 618) | (68 258–178 049) | |||||||||
| Western Pacific | 16 951 | 0·4–1·7 | 10% | 20 425 | 7·4–27·7 | 28% | 66 529 | 45·3–133·2 | 38% | 103 728 | 3·6–7·5 | 25% |
| (7197–28 946) | (8903–33 078) | (33 858–99 617) | (67 728–141 436) | |||||||||
| World Bank income classifications | ||||||||||||
| High income | 9531 | 0·5–1·5 | 6% | 9639 | 6·1–12·0 | 13% | 45 372 | 33·9–58·6 | 26% | 64 680 | 3·9–6·4 | 16% |
| (5312–16 208) | (7161–14 078) | (34 309–59 355) | (51 083–83 623) | |||||||||
| Upper middle income | 30 848 | 0·8–2·2 | 18% | 26 328 | 10·6–29·8 | 36% | 78 997 | 56·8–143·7 | 45% | 136 017 | 4·0–7·3 | 32% |
| (17 221–48 991) | (14 242–39 974) | (44 854–113 418) | (97 776–181 157) | |||||||||
| Lower middle income | 83 604 | 1·2–7·3 | 49% | 28 442 | 16·7–47·3 | 39% | 38 418 | 44·3–133·9 | 23% | 148 105 | 3·4–10·2 | 36% |
| (30 191–184 009) | (15 467–43 723) | (21 438–64 775) | (90 738–270 831) | |||||||||
| Low income | 45 848 | 0·8–13·9 | 26% | 7793 | 8·9–67·0 | 11% | 10 099 | 27·5–209·4 | 6% | 60 979 | 2·5–16·7 | 15% |
| (6731–119 752) | (2047–15 378) | (2980–22 685) | (22 143–150 010) | |||||||||
CrI=credible interval.
*
After applying our extrapolation approach to all countries, excess mortality rate (EMR)-contributing country extrapolated estimates were replaced with mean annual influenza-associated respiratory EMRs and death estimates, with the exception of Brazil and Kenya.
†
Estimates do not add up across all age groups because age-specific models were run separately and were not additive. Estimated proportions were calculated for each of 5000 extrapolation simulations and the median proportion from the 5000 simulations is presented.