Figure 4. Genetic components mapped onto the Fab structure of BLV5B8.

The rearranged genes (left) and their corresponding structural components (right) are color coded (blue, IGHV1-7; green, IGHD8-2; orange, IGHJ2-4, Pink, both IGLV30 and IGLJ3). In yellow is the area of V-D junction (labeled N) that encodes the ascending β-strand. This region is conserved and it is unclear whether it is derived from typical TdT catalyzed N-region insertions or other mechanisms like nucleotide capture. The C_H1 and C_λ regions are indicated on the right.