Figure 6.

Average measurements of the thickness of ocular tissues and compartments from a population of C57BL/6N mice, using OCT. Anterior segment OCT determined the central corneal thickness (88 ± 11 μm, n = 1466) and anterior chamber depth (411 ± 17 μm, n = 1506). The vitreous depth was assessed (530 ± 18 μm, n = 1698). Overall retinal thickness was measured (223 ± 5 μm, n = 1736). Segmentation of retinal layers, at the level of the optic nerve, quantified thicknesses of the inner plexiform layer (61 ± 4 μm, n = 1736), inner nuclear layer (29 ± 3 μm, n = 1736), outer nuclear layer (58 ± 3 μm, n = 1736), and photoreceptor inner/outer segments (40.0 ± 3 μm, n = 1736). Error bars (A) represent standard deviation. Examples of measurements of corneal thickness and anterior chamber depth (B) are shown. (C) An example of manual measurement of central vitreous depth is shown. (D) An example of measurement of retinal thickness and manual segmentation of retinal layers. N represents the number of eyes. Retina, total retinal thickness; segments, photoreceptor inner and outer segments.