Skip to main content
. Author manuscript; available in PMC: 2018 May 4.
Published in final edited form as: Lancet. 2017 Jan 17;389(10071):805–814. doi: 10.1016/S0140-6736(16)31588-4

Table 3.

Results of per-protocol analysis

Reference group UV group Bleach group Bleach and UV group
All target organisms

Exposed patients 4916 2848 5438 3701
Incident cases (%) 115 (2·3%) 46 (1·6%) 101 (1·9%) 93 (2·5%)
Exposure days 22 426 12 299 24 261 17 354
Rate (per 10 000 exposure-days) 51·3 37·4 41·6 53·6
Risk reduction (95% CI) Reference 13·9 (–0·1 to 27·9) 9·7 (–2·7 to 22·0) –2·3 (–15·7 to 11·1)
RR (95% CI); p value Reference 0·69 (0·50 to 0·95); 0·025 0·74 (0·61 to 0·91); 0·004 1·0 (0·81 to 1·23); 1·00

Clostridium difficile*

Exposed patients ·· ·· 2499 1712
Incident cases (%) ·· ·· 36 (1·4%) 30 (1·8%)
Exposure days ·· ·· 11 385 8015
Rate (per 10 000 exposure-days) ·· ·· 31·6 37·4
Risk reduction (95% CI) ·· ·· Reference –5·8 (–17·1 to 5·5)
RR (95% CI); p value ·· ·· Reference 1·22 (0·68 to 2·17); 0·511

Meticillin-resistant Staphylococcus aureus

Exposed patients 3300 1872 3631 2425
Incident cases (%) 73 (2·2%) 28 (1·5%) 74 (2·0%) 63 (2·6%)
Exposure days 14 525 7934 15 343 10 681
Rate (per 10 000 exposure-days) 50·3 35·3 48·2 59·0
Risk reduction (95% CI) Reference 15·0 (–0·6 to 30·6) 2·1 (–13·8 to 17·8) –8·7 (–18·0 to 0·5)
RR (95% CI); p value Reference 0·67 (0·48 to 0·94); 0·019 0·89 (0·72 to 1·09); 0·260 1·09 (0·85 to 1·39); 0·503

Vancomycin-resistant enterococci

Exposed patients 1055 659 1468 1134
Incident cases (%) 37 (3·5%) 13 (2·0%) 24 (1·6%) 24 (2·1%)
Exposure days 5838 3265 7522 6237
Rate (per 10 000 exposure-days) 63·4 39·8 31·9 38·5
Risk reduction (95% CI) Reference 23·6 (–6·1 to 53·2) 31·5 (12·7 to 50·2) 24·9 (–0·6 to 50·4)
RR (95% CI); p value Reference 0·56 (0·21 to 1·50); 0·248 0·35 (0·16 to 0·78); 0·010 0·41 (0·22 to 0·77); 0·006

Data are unchanged for multidrug-resistant Acinetobacter baumaunii (table 2).

*

Rooms with patients known or suspected of having C difficile infection were terminally cleaned with hypochlorite-containing solutions.