(A) Tumor volumes of different groups following three weeks of treatment. Black arrow head denotes time of ombrabulin (60 mg/kg) administration; orange arrow head denotes time of LP (1 mg/kg by dox) administration (* P < 0.05, ** P < 0.01, *** P < 0.005, two-way ANOVA with Bonferroni post test, n = 7 mice, s.e.). (B) Change in body weight of different groups following three weeks of treatment (n = 7 mice, s.e.). (C) Survival rate of different groups in the therapeutic efficacy study (** P < 0.01, log rank test; n = 7 mice).