Table 1.
Patient Characteristics and Tumor Staining
| Variable | Level | N (%) = 97 |
|---|---|---|
|
| ||
| Age | Median | 59.00 |
|
| ||
| p16 | negative | 28 (28.9) |
| positive | 69 (71.1) | |
|
| ||
| Gender | male | 81 (83.5) |
| female | 16 (16.5) | |
|
| ||
| Race | AA | 12 (12.4) |
| White | 79 (81.4) | |
| Other/Unknown | 6 (6.2) | |
|
| ||
| Smoking | never | 17 (17.7) |
| former | 41 (42.7) | |
| current | 38 (39.6) | |
|
| ||
| Differentiation | WD | 5 (5.2) |
| MD | 40 (41.2) | |
| NK | 52 (53.6) | |
|
| ||
| Tumor Stage | 1 | 39 (41.5) |
| 2 | 42 (44.7) | |
| 3–4 | 13 (13.8) | |
|
| ||
| Node Metastasis | N0–1 | 32 (33.3) |
| N2–3 | 64 (66.7) | |
|
| ||
| Overall Stage | 1–2 | 19 (22.6) |
| 3–4 | 65 (77.4) | |
|
| ||
| EGFR average overall | <= median (0.8) | 50 (52.6) |
| > median (0.8) | 45 (47.4) | |
|
| ||
| HER2 average overall | 0 | 71 (74.0) |
| 0.025–0.3 | 25 (26.0) | |
|
| ||
| HER3 average overall | <=median (0.1625) | 47 (49.5) |
| >median (0.1625) | 48 (50.5) | |
|
| ||
| PD-L1 | 0 | 71 (74.7) |
| 1–130 | 24 (25.3) | |
|
| ||
| PD-L2 | 0 | 33 (38.8) |
| 1–130 | 52 (61.2) | |
|
| ||
| PD-1+ lymphocytes in tumor | 0–1 | 33 (35.5) |
| 2–4 | 60 (64.5) | |
|
| ||
| PD-1+ lymphocytes in peritumoral stroma | 0–1 | 11 (11.8) |
| 2–4 | 82 (88.2) | |
AA African-American; WD well-differentiated; MD moderately differentiated; NK non-keratinized