Skip to main content
. Author manuscript; available in PMC: 2019 May 3.
Published in final edited form as: Cell Stem Cell. 2018 Apr 12;22(5):668–683.e6. doi: 10.1016/j.stem.2018.03.018

Figure 1. Single cell RNA-seq reveals a population of gland-like cells in the airway SE following naphthalene injury.

Figure 1

(A) Schematic of experimental design and single cell library preparation.

(B) t-SNE visualization of the single airway epithelial cells after naphthalene injury (n = 139 cells). Cells are color-coded by k-means clusters.

(C) Heat map of genes associated with the 5 clusters (Lum-1, Lum-2, Lum-3, Basal-1, and Basal-2). Values shown in terms of z-scores. Gene names in bold are individually featured in subsequent panels.

(D-I) t-SNE visualization of single airway epithelial cells after naphthalene injury (n = 139 cells). Cells are color coded by normalized expression of the indicated genes: (D) Krt5, (E) Krt8, (F) Scgb1a1, (G) Ltf, (lactoferrin) (H) Sox9, and (I) Acta2.

See also Figure S1.