Table 3.
Multivariable Associations of Social Network Indices with Clinical Factors
| Density | Betweenness | FSNI | ||||
|---|---|---|---|---|---|---|
| Model 1: For survivors and controls (N=204)† | ||||||
| Mean (SD) | T-statistic (P-value) | Mean (SD) | T-statistic (P-value) | Mean (SD) | T-statistic (P-value) | |
| Survivors | 0.42 (0.17) | −0.060 (0.802) | 0.50 (0.26) | −0.010 (0.929) | 11.22 (2.95) | 10.20 (0.002) |
| Controls | 0.43 (0.18) | 0.51 (0.27) | 9.85 (3.14) | |||
| Model 2: For survivors by cancer diagnoses (N=102)† | ||||||
| Beta | 95% CI (P-value) | Beta | 95% CI (P-value) | Beta | 95% CI (P-value) | |
| Diagnosis | ||||||
| CNS malignancy | Ref | Ref | Ref | Ref | Ref | Ref |
| Leukemia | 0.057 | −0.073, 0.188 (0.39) | −0.089 | −0.295, 0.117 (0.39) | 2.542 | 0.269, 4.815 (0.03) |
| Lymphoma | 0.057 | −0.075, 0.190 (0.39) | −0.099 | −0.309, 0.111 (0.351) | 2.765 | 0.451, 5.080 (0.020) |
| Solid tumor | 0.030 | −0.094, 0.153 (0.63) | −0.052 | −0.247, 0.143 (0.60) | 2.178 | 0.025, 4.331 (0.047) |
| Model 3: For survivors by therapeutic regimens (N=102)† | ||||||
| Beta | 95% CI (P-value) | Beta | 95% CI (P-value) | Beta | 95% CI (P-value) | |
| Chemotherapy | ||||||
| Yes | −0.009 | −0.079, 0.060 (0.80) | −0.033 | −0.143, 0.077 (0.55) | 1.362 | 0.139, 2.585 (0.03) |
| No | Ref | Ref | Ref | Ref | Ref | Ref |
| Radiotherapy | ||||||
| Yes | 0.050 | −0.022, 0.122 (0.17) | −0.083 | −0.196, 0.031 (0.15) | 0.493 | 0.773, 1.759 (0.44) |
| No | Ref | Ref | Ref | Ref | Ref | Ref |
†
Adjusted for age at study participation, sex, race/ethnicity, and education background in Models 2 and 3, but not in Model 1 as these covariates were balanced between survivors and controls (see Table 1)