Scheme 2.
Reagents and conditions: (a) LDA, THF, −78 °C, 30 min; (b) R1CHO, r.t., 16 h; (c) Et3SiH, TFA, DCM, r.t., 16 h; (d) 57% aq. HI, acetic acid, 100 °C, 4 h; *compound was purchased.
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