Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 4;8:7035. doi: 10.1038/s41598-018-24722-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

sEPSC frequency is significantly increased in CA3 pyramidal cells during OGD. (A) Representative traces from a control C57BL/6 mouse recorded at baseline, during OGD and during reoxygenation (reox) demonstrating an increase in spontaneous EPSC frequency during OGD. (B) Averaged data demonstrating that sEPSC frequency is significantly increased during OGD and returns to baseline levels during reox as a percent of baseline (n = 10 cells, 6 animals; baseline, Bsl: 1.4 ± 0.18 Hz; OGD: 2.08 ± 0.25 Hz; reox: 1.13 ± 0.19 Hz). *p < 0.05, K-W ANOVA. Data presented as percent mean ± SEM. (C) Representative inter-event cumulative frequency histogram demonstrating a reduction in the inter-event interval during OGD. (D) Representative amplitude cumulative histogram demonstrating no change in mEPSC amplitude during OGD. Inset showing averaged data for sEPSC amplitude at baseline, during OGD and during reox. (baseline, Bsl: 17.06 ± 1.14 pA; OGD: 16.57 ± 0.77 pA; reox: 15.72 ± 0.88 pA). Data presented as percent mean ± SEM. Baseline, solid line; OGD, dashed line; reox, dotted line.