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. 2018 May 4;8:7035. doi: 10.1038/s41598-018-24722-3

Figure 9.

Figure 9

UBP310 prevents the increase in mEPSC frequency during OGD. (A) Representative traces from a control C57BL/6 mouse recorded at baseline, during OGD and during reoxygenation (reox) demonstrating no change in mEPSC frequency during OGD. (B) Averaged data for mEPSC frequency during OGD and reox as a percent of baseline (n = 8 cells, 6 animals; baseline, Bsl: 0.49 ± 0.16 Hz; OGD: 0.46 ± 0.18 Hz; reox: 0.37 ± 0.15 Hz). (C) Representative inter-event cumulative frequency histogram showing no change in the inter-event intervals during OGD and reox. (D) Representative amplitude cumulative histogram demonstrating no change in mEPSC amplitude during OGD. Inset showing averaged data for mEPSC amplitude during OGD and reox as a percent of baseline (baseline, Bsl: 13.0 ± 1.74 pA; OGD: 13.19 ± 1.9 pA; reox: 15.03 ± 2.21 pA). Data presented as percent mean ± SEM. Baseline, solid line; OGD, dashed line; reox, dotted line.