Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 4;8:7039. doi: 10.1038/s41598-018-25468-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

IP6K1 deletion disrupted apical ectoplasmic specialization. (a–e) Evaluation of spermatids by electron microscopy. (a) No characteristic apical ectoplasmic specialization (aES) was observed in step 8 spermatids of IP6K1 KOs (inset). Scale bar 500 nm. (b) The aES was not well formed in step 10 spermatids of IP6K1 KOs (arrows). ER: endoplasmic reticulum; nu: nucleus. Scale bar 100 nm. (c) Disorganized aES was seen in step 12 spermatids of IP6K1 KOs (arrows). ER: endoplasmic reticulum; nu: nucleus. Scale bar 100 nm. (d) Apical ES was collapsing in step 14 spermatids of IP6K1 KOs. ER: endoplasmic reticulum; nu: nucleus. Scale bar 100 nm. (e) Apical ES collapsed in step 16 spermatids of IP6K1 KOs (arrows). ER: endoplasmic reticulum; nu: nucleus. Scale bar 100 nm. (f and g) The actin surrounding spermatids were decreased in IP6K1 KOs. Staining of F-actin by phalloidin on seminiferous tubules. Scale bar 20μm in (f); scale bar 5μm in (g).