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. 2018 May 4;8:7080. doi: 10.1038/s41598-018-25443-3

Table 3.

The correlations between nuclear HuR expression and the clinical features of GC patients. P value < 0.05 was indicated in bold.

Variable N Nuclear HuR expression P value
HuR-high % HuR-low %
Sex 251
Male 178 116 65.2 62 34.8 0.613
Female 73 50 68.5 23 31.5
Age
 <60 80 49 61.2 31 38.8 0.263
 ≥60 171 117 68.4 54 31.6
Depth of invasion
 T1-T3 82 47 57.3 35 42.7 0.040
 T4 169 119 70.4 50 29.6
Lymph node metastasis
 Absent (N0) 104 63 60.6 41 39.4 0.118
 Present (N1-N3) 147 103 70.1 44 29.9
Distant metastasis
 M0 226 146 64.6 80 35.4 0.123
 M1 25 20 80.0 5 20
TNM Stage
 1 + 2 116 67 57.8 49 42.2 0.009
 3 + 4 135 99 73.3 36 26.7
Tumor size (cm)
 >5 93 70 75.3 23 24.7 0.019
 ≤5 158 96 60.8 62 39.2
Differentiation status
 Well/Moderate 147 95 64.6 52 35.4 0.548
 Poor/Undifferentiated 104 71 68.3 33 31.7
TTP-expression
 TTP-high 101 58 57.4 43 42.6 0.017
 TTP-low 150 108 72.0 42 28.0
Cytoplasmic HuR
 Positive 81 58 71.6 23 28.4 0.206
 Negative 170 108 63.5 62 36.5