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. 2018 Feb 14;3(2):174–185. doi: 10.1016/j.bioactmat.2018.01.003

Table 3.

Available in vitro recommendations observing the V/A ratio to apply.

DIN EN ISO 10993-12 (2007)
Biological evaluation of medical devices - Part 12: Sample preparation and reference materials
Volume/area (mL/cm2) ± 10% 0.17–0.8 (depending on the shape)
Volume/mass (mL/g) ± 10% 5–10 (depending on the shape)
ASTMG31-72(2004)
Standard Practice for Laboratory Immersion Corrosion Testing of Metals
Volume/area (mL/cm2) 20–40