Table 2.
Sex differences in overall post LT outcomes.
Outcome | Sex difference | Comment |
---|---|---|
Patient/graft survival | Controversial | German study identified higher 90-day mortality in women [20]. U.S. study did not identify sex difference [21] |
Rejection risk | No | No overall sex difference in acute or chronic rejection [29-31] though higher risk of early acute rejection in women with HCV [28]. Women less likely to wean from IMS and develop immune tolerance [25] |
Quality of life | Yes | Considerable variability in the definition of specific QOL indicators though differences in sexual function, emotional and physical well-being are apparent |
Renal function | Yes | Women at higher risk of CKD post LT [16,32-34] |
Post LT recovery and sarcopenia | Yes | In men, but less so women, sarcopenia is associated with worse post LT survival and post operative recovery [36-37] |