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. 2015 Nov 18;2:34–53. doi: 10.1016/j.conctc.2015.10.002

Table 1.

Hypothetical Distributions of a HDRS17 Subscale Score based on an Early Phase 2 Major Depressive Disorder Trial using a DRDS Design with Parameter Values: r1 = 2, π = 0.60, γ = 0.40, r2 = 1.

Period 1
μ1T σ1T μ1P σ1P Δ1 σ1
3.30
2.44
3.00
2.40
0.30
2.42
Period 2
μ2T
σ2T
μ2P
σ2P
Δ2
σ2
3.90 1.95 2.80 2.00 1.10 1.98