Table 1.
Hypothetical Distributions of a HDRS17 Subscale Score based on an Early Phase 2 Major Depressive Disorder Trial using a DRDS Design with Parameter Values: r1 = 2, π = 0.60, γ = 0.40, r2 = 1.
Period 1 | |||||
---|---|---|---|---|---|
μ1T | σ1T | μ1P | σ1P | Δ1 | σ1 |
3.30 |
2.44 |
3.00 |
2.40 |
0.30 |
2.42 |
Period 2 | |||||
μ2T |
σ2T |
μ2P |
σ2P |
Δ2 |
σ2 |
3.90 | 1.95 | 2.80 | 2.00 | 1.10 | 1.98 |