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. 2018 Apr 15;7(4):bio033944. doi: 10.1242/bio.033944

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© 2018. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — A ciliated cell-specific transcriptome for the developing mouse airways. (A) Diagram illustrating the lineage relationships between cells in the embryonic lung. Rectangles denote cell populations isolated for microarray analysis. (B) GO analysis of transcripts enriched >3-fold in the E17.5 FOXJ1-GFP⁺ cells compared with the E11.5 tip progenitors showed that categories associated with cilia were highly enriched compared with their frequency in the reference genome. (C) mRNA in situ hybridisation for Foxj1, Mlf1, Tp73, Zcchc12, Dlx4, Hipk3, Hes6, Nr4a3, Casz1 and Sox1 in the E17.5 stage mouse airways. Scale bars: 100 μm; 50 μm in insets.