Skip to main content
. Author manuscript; available in PMC: 2018 May 30.
Published in final edited form as: Nature. 2017 Nov 22;551(7682):629–633. doi: 10.1038/nature24620

Extended Data Figure 10. Activation of germ cell metabolism.

Extended Data Figure 10

a, Immature germ cells arrest with a high ATP:ADP ratio and a high energy charge, which are reversed in response to sperm signals as ADP levels rise and unlock the ATP synthase. These changes reflect a shift from a resting to an active metabolic state22,23. b, 488 nm-excited fluorescence of PercevalHR and cpmVenus. c, Heatmap of the PercevalHR λhigh/λlow ratio after vha-13 knockdown. d, Peredox fluorescence in a hermaphrodite germline, with line profiles. e, f, GFP::GLD-1 and mitochondrial morphology in ADP- or vehicle-injected female oocytes. Bars, 10 µm.