TABLE 5.
Multivariable models of the association between race/ethnicity and ABO-nonidentical transplantation
| Univariable analysis | Multivariable modelsa | |||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Model 1 | Model 2 | Model 3 | ||||||
|
|
|
|
|
|||||
| sHR (95% CI) | P-value | sHR(95%CI) | P-value | sHR(95%CI) | P-value | sHR(95%CI) | P-value | |
| Race/ethnicity | ||||||||
|
| ||||||||
| Non-Hispanic White | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
|
| ||||||||
| Black | 1.61 (1.32–1.98) | <.001 | 1.30 (1.06–1.62) | .013 | 1.30 (1.05–1.61) | .016 | 0.82 (0.65–1.01) | .067 |
|
| ||||||||
| Hispanic | 0.91 (0.74–1.13) | .40 | 0.85 (0.68–1.04) | .12 | 0.90 (0.73–1.12) | .35 | 1.05 (0.84–1.31) | .67 |
|
| ||||||||
| Asian | 1.54 (1.15–2.05) | .003 | 1.63 (1.18–2.25) | .003 | 1.70 (1.22–2.36) | .001 | 0.72 (0.51–1.03) | .074 |
|
| ||||||||
| Other | 1.40 (0.86–2.31) | .18 | 1.28 (0.77–2.12) | .34 | 1.31 (0.79–2.17) | .30 | 1.37 (0.80–2.32) | .25 |
|
| ||||||||
| Region | ||||||||
|
| ||||||||
| Low MELD (<28) | Ref | Ref | Ref | Ref | ||||
|
| ||||||||
| Medium MELD (28–30) | 1.07 (0.88–1.30) | .51 | 0.88 (0.72–1.08) | .23 | ||||
|
| ||||||||
| High MELD (>30) | 0.83 (0.71–0.98) | .025 | 0.72 (0.61–0.85) | <.001 | ||||
|
| ||||||||
| Recipient ABO Status | ||||||||
|
| ||||||||
| O | Ref | Ref | ||||||
|
| ||||||||
| A | 0.68 (0.52–0.90) | .007 | ||||||
|
| ||||||||
| B | 11.6 (9.43–14.1) | <.001 | ||||||
|
| ||||||||
| AB | 29.3 (23.5–36.5) | <.001 | ||||||
N=27 324 in each model.
a
Each model is also adjusted for recipient age, sex, etiology of liver disease, exception points granted, initial laboratory Model for End-Stage Liver Disease (MELD) score, and listing center volume.