Figure 5.
Specific lysis of SIINFEKL-loaded splenocytes 24 h after intravenous injection in (A) spleen, (B) draining lymph nodes, and (C) blood in naïve mice and following subcutaneous immunization with 1 μg/dose OVA, OVA/cationic adjuvant formulation (CAF)09, and OVA/CAF24a, respectively. (D) Comparison of the levels of SIINFEKL-specific CD8+ T cells and the specific lysis in the blood in individual mice. Correlation for the combined groups: Spearman, p = 0.0001. The results are from one of two repeated studies. n = 6, lines with bars represent mean ± SEM. *p ≤ 0.05, **p ≤ 0.01, ****p ≤ 0.0001, one-way ANOVA with Tukey’s post-test.