FIGURE 2.

HPLC traces of the extracts from strains R818 (A) and J378 (B). Metabolites/peaks elicited or enhanced by the rare earth salt LaCl₃ (labeled as “-la”) were highlighted by red dashed boxes. Absorbance was recorded at UV = 254 nm. Inset in A, the typical UV spectrum of the LaCl₃-activated metabolites in R818; a representative peak marked by an asterisk (compound 1, RT = 9.25 min) was purified and identified as urauchimycin D. The inhibition zone of 1 against C. albicans was measured as 16 mm.