Table 2.
Identification of novel interactors with 14-3-3 proteins
The information in this table is compared to the data of Johnson et al. (14). There is a total of 56 novel interactors.
| Uniprot | Description | Gene name | Previously reported to interact with 14-3-3ζ |
|---|---|---|---|
| Q8VDD5 | Myosin-9 | Myh9 | Yes |
| Q4FK11 | Non-POU-domain-containing, octamer binding protein | Nono | No |
| E9QMZ5 | Plectin | Plec | No |
| E9QPE8 | Plectin | Plec | No |
| G5E8B8 | Anastellin | Fn1 | No |
| Q61879 | Myosin-10 | Myh10 | Yes |
| P97855 | Ras GTPase-activating protein-binding protein 1 | G3bp1 | Yes |
| P61979 | Heterogeneous nuclear ribonucleoprotein K | Hnrnpk | Yes |
| Q9R002 | Interferon-activable protein 202 | Ifi202 | No |
| B7FAU9 | Filamin, α | Flna | No |
| Q61033 | Lamina-associated polypeptide 2, isoforms α/ζ | Tmpo | Yes |
| B2RSN3 | MCG1395 | Tubb2b | Yes |
| Q91VR5 | ATP-dependent RNA helicase DDX1 | Ddx1 | Yes |
| P48962 | ADP/ATP translocase 1 | Slc25a4 | Yes |
| P51881 | ADP/ATP translocase 2 | Slc25a5 | Yes |
| Q60865 | Caprin-1 | Caprin1 | Yes |
| Q8BMK4 | Cytoskeleton-associated protein 4 | Ckap4 | Yes |
| B8JJG1 | Novel protein (2810405J04Rik) | Fam98a | No |
| Q61029 | Lamina-associated polypeptide 2, isoforms β/δ/ϵ/γ | Tmpo | Yes |
| Q8VIJ6 | Splicing factor, proline- and glutamine-rich | Sfpq | Yes |
| P62702 | 40S ribosomal protein S4, X isoform | Rps4x | Yes |
| Q3TQX5 | DEA(D/H) (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked | Ddx3x | No |
| Q4VA29 | MCG140066 | 2700060E02Rik | No |
| P14148 | 60S ribosomal protein L7 | Rpl7 | Yes |
| Q3UMM1 | Tubulin, β6 | Tubb6 | No |
| G3UXT7 | RNA-binding protein FUS (fragment) | Fus | No |
| Q8VEM8 | Phosphate carrier protein, mitochondrial | Slc25a3 | Yes |
| E9QPE7 | Myosin-11 | Myh11 | No |
| A2A547 | Ribosomal protein L19 | Rpl19 | No |
| P63038 | 60-kDa heat shock protein, mitochondrial | Hspd1 | Yes |
| D3Z6C3 | Protein Gm10119 | Gm10119 | No |
| Q9DB20 | ATP synthase subunit O, mitochondrial | Atp5o | Yes |
| O70475 | UDP-glucose 6-dehydrogenase | Ugdh | No |
| A2APD4 | Small nuclear ribonucleoprotein-associated protein | Snrpb | No |
| O70309 | Integrin β5 | Itgb5 | No |
| G3UZI2 | Heterogeneous nuclear ribonucleoprotein Q | Syncrip | No |
| D3Z6U8 | Fragile X mental retardation protein 1 homolog | Fmr1 | No |
| O35841 | Apoptosis inhibitor 5 | Api5 | No |
| A4FUS1 | MCG123443 | Rps16 | No |
| Q3TLH4-5 | Isoform 5 of protein PRRC2C | Prrc2c | No |
| P14869 | 60S acidic ribosomal protein P0 | Rplp0 | Yes |
| Q8QZY1 | Eukaryotic translation initiation factor 3 subunit L | Eif3l | No |
| P35922 | Fragile X mental retardation protein 1 homolog | Fmr1 | Yes |
| Q03265 | ATP synthase subunit α, mitochondrial | Atp5a1 | Yes |
| P63017 | Heat shock cognate 71-kDa protein | Hspa8 | Yes |
| P21981 | Protein-glutamine γ-glutamyltransferase 2 | Tgm2 | Yes |
| Q80UM7 | Mannosyl-oligosaccharide glucosidase | Mogs | Yes |
| P26369 | Splicing factor U2AF 65-kDa subunit | U2af2 | No |
| A2AJM8 | MCG7378 | Sec61b | No |
| P62242 | 40S ribosomal protein S8 | Rps8 | Yes |
| P54823 | DEA(D/H) (Asp-Glu-Ala-Asp/His) box polypeptide 6 | Ddx6 | Yes |
| Q3TML6 | Eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked | Eif2s3x | No |
| P26041 | Moesin | Msn | Yes |
| P62983 | Ubiquitin-40S ribosomal protein S27a | Rps27a | Yes |
| P52480 | Pyruvate kinase isozymes M1/M2 | Pkm2 | Yes |
| Q5SUT0 | Ewing sarcoma breakpoint region 1 | Ewsr1 | No |
| E9Q7H5 | Uncharacterized protein | Gm8991 | No |
| Q8C2Q8 | ATP synthase γ chain | Atp5c1 | No |
| A2AMW0 | Capping protein (actin filament) muscle Z-line, β | Capzb | No |
| P08121 | Collagen α-1(III) chain | Col3a1 | Yes |
| P11087-2 | Isoform 2 of collagen α-1(I) chain | Col1a1 | Yes |
| Q9Z2X1-2 | Isoform 2 of heterogeneous nuclear ribonucleoprotein F | Hnrnpf | Yes |
| P11499 | Heat shock protein HSP 90β | Hsp90ab1 | Yes |
| P28301 | Protein-lysine 6-oxidase | Lox | Yes |
| Q8VCQ8 | Caldesmon 1 | Cald1 | No |
| P27659 | 60S ribosomal protein L3 | Rpl3 | Yes |
| O35737 | Heterogeneous nuclear ribonucleoprotein H | Hnrnph1 | Yes |
| A2ACG7 | Dolichyl-diphosphooligosaccharide–protein glycosyltransferase subunit 2 | Rpn2 | No |
| Q3TVI8 | Pre-B-cell leukemia transcription factor-interacting protein 1 | Pbxip1 | No |
| F6QCI0 | Protein Taf15 (fragment) | Taf15 | No |
| O88569-3 | Isoform 3 of Heterogeneous nuclear ribonucleoproteins A2/B1 | Hnrnpa2b1 | Yes |
| O08583-2 | Isoform 2 of THO complex subunit 4 | Alyref | Yes |
| O08573-2 | Isoform short of galectin-9 | Lgals9 | Yes |
| Q564E8 | Ribosomal protein L4 | Rpl4 | No |
| B1ARA3 | 60S ribosomal protein L26 (Fragment) | Rpl26 | No |
| O35129 | Prohibitin-2 | Phb2 | Yes |
| D3YTQ9 | 40S ribosomal protein S15 | Rps15 | No |
| Q6ZWX6 | Eukaryotic translation initiation factor 2 subunit 1 | Eif2s1 | Yes |
| D3Z3R1 | 60S ribosomal protein L36 | Gm5745 | No |
| P17427 | AP-2 complex subunit α2 | Ap2a2 | No |
| P56480 | ATP synthase subunit β, mitochondrial | Atp5b | Yes |
| Q8CBM2 | Aspartate-β-hydroxylase | Asph | No |
| Q6NVF9 | Cleavage and polyadenylation specificity factor subunit 6 | Cpsf6 | Yes |
| Q5SQB0 | Nucleophosmin | Npm1 | No |
| Q6A0A9 | Constitutive coactivator of PPARγ-like protein 1 | FAM120A | Yes |
| P14576 | Signal recognition particle 54-kDa protein | Srp54 | No |
| P63087 | Serine/threonine-protein phosphatase PP1γ catalytic subunit | Ppp1cc | Yes |
| P80315 | T-complex protein 1 subunit δ | Cct4 | Yes |
| P62960 | Nuclease-sensitive element-binding protein 1 | Ybx1 | Yes |
| P97376 | Protein FRG1 | Frg1 | No |
| Q3U4Z7 | High-density lipoprotein-binding protein, isoform CRA_d | Hdlbp | No |
| B2RTB0 | MCG17262 | Pdap1 | No |
| P60335 | Poly(rC)-binding protein 1 | Pcbp1 | Yes |
| P47911 | 60S ribosomal protein L6 | Rpl6 | Yes |
| Q61990-2 | Isoform 2 of Poly(rC)-binding protein 2 | Pcbp2 | Yes |
| P62267 | 40S ribosomal protein S23 | Rps23 | Yes |
| D3Z148 | Caveolin (Fragment) | Cav1 | No |
| P84084 | ADP-ribosylation factor 5 | Arf5 | Yes |
| O54724 | Polymerase I and transcript release factor | Ptrf | Yes |
| E9Q132 | 60S ribosomal protein L24 | Rpl24 | No |
| O54890 | Integrin β-3 | Itgb3 | No |
| O88477 | Insulin-like growth factor 2 mRNA-binding protein 1 | Igf2bp1 | Yes |
| P61750 | ADP-ribosylation factor 4 | Arf4 | Yes |
| Q9CR67 | Transmembrane protein 33 OS | Tmem33 | Yes |
| Q5XJF6 | Ribosomal protein L10a | Rpl10a | No |
| Q3THB3 | Heterogeneous nuclear ribonucleoprotein M | Hnrnpm | No |
| Q6P5B5 | Fragile X mental retardation syndrome-related protein 2 | Fxr2 | No |
| D3Z6S1 | Uncharacterized protein | Tmem214 | No |
| P11152 | Lipoprotein lipase | Lpl | Yes |
| Q9DCR2 | AP-3 complex subunit σ1 | Ap3s1 | No |
| P59999 | Actin-related protein 2/3 complex subunit 4 | Arpc4 | Yes |
| P49312 | Heterogeneous nuclear ribonucleoprotein A1 | Hnrnpa1 | Yes |
| P61358 | 60S ribosomal protein L27 | Rpl27 | Yes |
| O54734 | Dolichyl-diphosphooligosaccharide–protein glycosyltransferase 48-kDa subunit | Ddost | Yes |
| Q07235 | Glia-derived nexin | Serpine2 | No |
| Q7TNV0 | Protein DEK | Dek | Yes |
| Q922B2 | Aspartate–tRNA ligase, cytoplasmic | Dars | No |
| P62320 | Small nuclear ribonucleoprotein Sm D3 | Snrpd3 | Yes |
| P15864 | Histone H1.2 | Hist1h1c | Yes |
| Q8R0W0 | Epiplakin | Eppk1 | No |
| Q6ZQ38 | Cullin-associated NEDD8-dissociated protein 1 | Cand1 | Yes |