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. 2018 Mar 14;293(18):6925–6941. doi: 10.1074/jbc.RA118.002566

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© 2018 Peoples et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 1. — Steady-state ATP concentrations compared with rates of ATP synthesis and hydrolysis in E11.5 isolated adrenergic hormone-deficient hearts compared with controls. A, steady-state ATP concentrations in adrenergic hormone-competent (●) and adrenergic hormone-deficient (□) embryonic hearts at embryonic day 11.5. B and D, ATP synthesis rate in adrenergic hormone-competent (●) and adrenergic hormone-deficient (□) embryonic hearts, expressed as relative light units (RLUs) produced/s and fold-change, respectively. C and E, ATP hydrolysis rates in adrenergic hormone-competent (●) and adrenergic hormone-deficient (□) embryonic hearts expressed as absorbance/s and fold-change, respectively. Numerical values below the x axes refer to the number (n) of samples analyzed. Data are presented as fold-change compared with competent control littermates. Student's t test was used to compare means between competent and deficient groups. **, p < 0.01.