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In vitro calcein delivery in porcine skin. The MNs were penetrated into the skin to a depth of 600 µm. The left side shows calcein delivery via porous polymer-coated MNs, whereas the right side shows delivery via non-coated MNs. h1 represents the top skin section, whereas h15 represents the deepest section for which calcein was detected. Calcein was delivered to depths of 750 and 100 µm by the porous-coated and non-coated MNs, respectively.
