Table 1.
In vitro anti-tubercular activity of chromone embedded [1,2,3]-triazoles against Mycobacterium tuberculosis H37Rv.
| MIC | MIC | ||||||
|---|---|---|---|---|---|---|---|
| entry | compound | (μg ml−1)a | cytotoxicityb | entry | compound | (μg ml−1)a | cytotoxicityb |
| 6a |  |
25 | 12.86 | 6k |  |
50 | 26.12 |
| 6b |  |
25 | 26.82 | 6l |  |
50 | 30.60 |
| 6c |  |
25 | 16.12 | 6m |  |
6.25 | 36.82 |
| 6d |  |
50 | 20.60 | 6n |  |
50 | 23.74 |
| 6e |  |
25 | 20.12 | 6o |  |
3.125 | 18.42 |
| 6f |  |
3.125 | 20.12 | 6p |  |
12.5 | 20.12 |
| 6g |  |
6.25 | 28.40 | 6q |  |
25 | 28.62 |
| 6h |  |
3.125 | 18.68 | 6r |  |
50 | 30.60 |
| 6i |  |
25 | 26.82 | 6s |  |
1.56 | 24.68 |
| 6j |  |
50 | 30.34 | 6t |  |
50 | 30.12 |
aRifampicin (MIC, 0.24 µg ml−1); ethambutol (MIC, 7.64 µg ml−1).
bCytotoxicity at 50 µg ml−1 (RAW 264.7 cells).