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. 2018 Apr 30;12:281. doi: 10.3389/fnins.2018.00281

Figure 4.

Figure 4

Overexpression of DGCR8 promotes NPC expansion (A–D) Immunostaining for PAX6 (A, green) or TBR2 (C, green) and mCherry+ electroporated cells (A,C, red) and merged images on coronal cryosections through the dorsal telencephalon of Control and DGCR8 OE mouse embryos at E14.5 after IUEp at E12.5, and quantification of the proportion of PAX6+ mCherry+ (B) or TBR2+ mCherry+ (D) cells expressed in % over total mCherry+ cells. SVZ: subventricular zone and VZ: ventricular zone: scale bar: 20 μm. Error bars indicate the variation of five Control and four DGCR8 OE electroporated cortices (s.e.m.); unpaired Student's t-test. **p-value < 0.01; ***p-value < 0.001.