TABLE 2.
Analysis of napsin A-positive large cell neuroendocrine carcinomas in whole-tissue sections.
| Napsin A | TTF-1 | Synapto-physin | Chromo-granin | CD56 | Ki-67 | ||
|---|---|---|---|---|---|---|---|
| Percentage | Intensity | ||||||
| Case 1 | 10% | 1+ | Dif | Dif | Foc | 0 | 40% |
| Case 2 | 50% | 1.5+ | Dif | Dif | 0 | 0 | 50% |
| Case 3 | 5% | 1.5+ | Dif | Dif | Dif | Dif | 50% |
| Case 4 | 70% | 1.5+ | Dif | Foc | 0 | Dif | 80% |
| Case 5 | 10% | 1+ | Dif | Dif | Foc | 0 | 50% |
| Case 6 | 10% | 1+ | Dif | Dif | Dif | Foc | 50% |
| Case 7 | 10% | 1.5+ | Dif | Foc | Foc | Dif | 60% |
| Case 8 | 5% | 1+ | Foc | Dif | Dif | 0 | 50% |
| Case 9 (ID 42)* | 10% | 2+ | na | Dif | 0 | na | 50% |
| Case 10 (ID 49)* | 90% | 2+ | Dif | Dif | Dif | na | 40% |
| Case 11 (ID 28)* | 20% | 1+ | Dif | Dif | 0 | Dif | 80% |
| Case 12 (ID 32)* | 80% | 2+ | Dif | Dif | 0 | Dif | 80% |
| Case 13 (ID 59)* | 90% | 2+ | Dif | Dif | Dif | 0 | 60% |
| Case 14 (ID 38)* | 70% | 1.5+ | Dif | Dif | 0 | Dif | 70% |
| Case 15 (ID 40)* | 20% | 1.5+ | Dif | Dif | Foc | Foc | 80% |
| Case 16 (ID 39)* | 10% | 1+ | Dif | Dif | Dif | Dif | 70% |
| Case 17 (ID 64)* | 20% | 1+ | Dif | Foc | Foc | Foc | 50% |
| Summary |
Mean±SD: 34±32% |
Mean±SD: 1.4±0.4 |
% positive: 100% |
% positive: 100% |
% positive: 65% |
% positive: 67% |
Mean±SD: 60±14% |
Foc = focal (≤50% tumor cells labeling), Dif = diffuse (>50% tumor cells labeling), na = not available
*
Shown in parenthesis are corresponding case IDs from Rekhtman et al6.