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Effect sizes and consequences of top variants. (A) Allele frequencies and effect sizes for all variants with Bayes-GLMM-derived P < 1 × 10−6. Positive-effect (i.e., risk-increasing) loci are in red and negative-effect loci (i.e., protective) are in blue. (B) Functional consequences of the top variants. MAF, minor allele frequency.
