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. 2018 May 3;209(1):51–64. doi: 10.1534/genetics.117.300673

Table 1. Top 55 variants with P < 1 × 10−6.

RSID Chromosome Position Reference Alternate MAF Effect size SD 95% C.I. P-value
rs74944275 5 102,726,073 C T 0.019 2.371 0.394 [1.633, 3.136] 1.76 × 10−9
rs10490263 2 40,973,289 C T 0.469 0.697 0.116 [0.483, 0.932] 2.15 × 10−9
rs149372995 7 580,540 A G 0.051 1.532 0.269 [0.992, 2.063] 1.18 × 10−8
rs140233081 7 580,735 C A 0.056 1.396 0.255 [0.926, 1.898] 4.26 × 10−8
rs139258867 11 33,422,464 C T 0.017 2.487 0.461 [1.593, 3.418] 6.89 × 10−8
rs11709639 3 94,975,203 T A 0.325 0.645 0.120 [0.415, 0.875] 8.61 × 10−8
rs75841969 12 127,335,883 G A 0.052 1.464 0.275 [0.921, 2.007] 1.05 × 10−7
rs72720587 4 137,323,780 C T 0.019 2.328 0.441 [1.515, 3.221] 1.27 × 10−7
rs2018116 14 92,831,272 T C 0.768 0.636 0.121 [0.383, 0.855] 1.41 × 10−7
rs141404567 11 33,393,524 G A 0.017 2.514 0.481 [1.634, 3.425] 1.70 × 10−7
rs2010568 2 118,395,972 G C 0.429 0.646 0.125 [0.385, 0.882] 2.38 × 10−7
rs144152209 7 585,369 C A 0.060 1.349 0.262 [0.879, 1.872] 2.49 × 10−7
rs74917009 5 169,915,787 G A 0.027 1.971 0.382 [1.233, 2.661] 2.54 × 10−7
rs144990130 7 582,328 G A 0.061 1.324 0.257 [0.849, 1.823] 2.65 × 10−7
rs12685122 9 9,206,006 T G 0.211 0.867 0.169 [0.534, 1.196] 2.95 × 10−7
rs73046027 3 19,950,385 C T 0.132 0.963 0.188 [0.624, 1.349] 3.18 × 10−7
rs7463321 8 20,523,821 T C 0.167 0.860 0.168 [0.523, 1.198] 3.23 × 10−7
rs148758667 9 130,665,077 G T 0.060 1.456 0.285 [0.949, 2.026] 3.30 × 10−7
rs72618491 3 94,938,828 G A 0.335 0.606 0.119 [0.363, 0.85] 3.31 × 10−7
rs117662279 7 155,362,626 G A 0.018 2.214 0.434 [1.328, 3.048] 3.34 × 10−7
rs1280103 4 187,526,002 C A 0.396 −0.627 0.123 [−0.878, −0.388] 3.63 × 10−7
rs7856285 9 18,973,653 G A 0.609 0.612 0.120 [0.366, 0.84] 3.65 × 10−7
rs17383917 3 94,984,650 T C 0.330 0.640 0.126 [0.401, 0.879] 4.08 × 10−7
rs11124760 2 41,001,812 C T 0.437 0.639 0.126 [0.394, 0.884] 4.15 × 10−7
rs61768273 1 44,509,818 A T 0.034 1.790 0.354 [1.074, 2.443] 4.25 × 10−7
rs17383687 3 94,963,466 C T 0.329 0.653 0.129 [0.412, 0.924] 4.33 × 10−7
rs12497549 3 20,072,654 C T 0.157 0.898 0.178 [0.528, 1.251] 4.52 × 10−7
rs36147593 15 27,587,764 A G 0.110 1.119 0.222 [0.684, 1.539] 4.86 × 10−7
rs10933941 3 94,965,589 G A 0.329 0.635 0.126 [0.392, 0.888] 4.98 × 10−7
rs116407196 5 102,973,337 A G 0.035 1.804 0.360 [1.129, 2.524] 5.25 × 10−7
rs7122488 11 21,874,253 T C 0.646 0.633 0.126 [0.402, 0.868] 5.26 × 10−7
rs12639003 3 94,966,599 A G 0.329 0.637 0.127 [0.39, 0.878] 5.35 × 10−7
rs12549162 8 20,547,331 C G 0.167 0.872 0.174 [0.538, 1.216] 5.50 × 10−7
rs62483581 7 106,726,214 G A 0.451 0.587 0.117 [0.367, 0.837] 5.52 × 10−7
rs12485639 3 94,940,998 C A 0.320 0.604 0.121 [0.359, 0.841] 5.55 × 10−7
rs67822265 2 53,715,939 C T 0.289 0.665 0.133 [0.401, 0.933] 5.70 × 10−7
rs17383861 3 94,983,399 G A 0.331 0.635 0.127 [0.396, 0.876] 5.91 × 10−7
rs9826288 3 95,044,652 C T 0.665 −0.618 0.124 [−0.855, −0.369] 6.27 × 10−7
rs2478319 13 48,111,575 A G 0.689 0.596 0.120 [0.358, 0.821] 6.33 × 10−7
rs72720573 4 137,257,730 T C 0.018 2.416 0.485 [1.488, 3.359] 6.46 × 10−7
rs140419591 11 33,327,476 A G 0.017 2.516 0.506 [1.553, 3.502] 6.54 × 10−7
rs78491489 7 44,335,828 C T 0.113 0.934 0.188 [0.61, 1.321] 6.80 × 10−7
rs6689933 1 76,837,471 C T 0.684 0.633 0.128 [0.401, 0.876] 7.47 × 10−7
rs17263248 3 55,574,820 A G 0.200 0.804 0.163 [0.5, 1.13] 7.54 × 10−7
rs10435819 9 9,197,298 G A 0.194 0.849 0.172 [0.49, 1.165] 7.58 × 10−7
rs61446477 3 94,964,689 A G 0.329 0.639 0.129 [0.38, 0.887] 7.73 × 10−7
rs72720589 4 137,333,269 T A 0.017 2.233 0.452 [1.326, 3.105] 7.80 × 10−7
rs7978950 12 47,361,547 C T 0.412 0.611 0.124 [0.382, 0.858] 7.92 × 10−7
rs2176276 3 94,989,440 C A 0.329 0.613 0.124 [0.389, 0.856] 8.13 × 10−7
rs1359665 13 48,097,289 G A 0.684 0.642 0.130 [0.384, 0.887] 8.16 × 10−7
rs4849593 2 118,369,787 G A 0.407 0.652 0.132 [0.404, 0.917] 8.20 × 10−7
rs72618501 3 94,974,822 T C 0.330 0.633 0.129 [0.398, 0.881] 8.66 × 10−7
rs61768270 1 44,498,974 C T 0.034 1.788 0.364 [1.134, 2.481] 8.88 × 10−7
rs1861305 2 40,950,582 A G 0.468 0.589 0.120 [0.356, 0.819] 8.96 × 10−7
rs4367173 4 7,383,470 C G 0.195 −0.664 0.136 [−0.92, −0.4] 9.58 × 10−7

Variants in italics met a standard genome-wide significance of P < 5 × 10−8. RSID, reference SNP cluster identifier; MAF, minor allele frequency.