. 2018 Mar 13;209(1):265–279. doi: 10.1534/genetics.118.300908

Table 2. Main results of “context-independent” models^a and the present model (FGM) when stress only affects $r_{D}$ (only shifts the optimum position in our model).

	Context-Independent Model	FGM Rescue Model
Impact of decay rate $r_{D}$	$ω_{D N} \propto r_{D}^{- 1},$ $ω_{S V} = constant$	$ω \propto e^{- r_{D}^{2}} r_{D}^{- 3}$ ⁽¹⁾
Impact of mutational input $N_{0} U$	$ω \propto N_{0} U$	$ω \propto N_{0} U$
“Characteristic decay rate” ( $r_{D}^{c}$ ) for DN rescue vs. $N_{0} U$	$r_{D}^{c} \propto N_{0} U$	$r_{D}^{c} \propto \sqrt{\log (N_{0} U)}$
Relative contribution of standing variance to ER	Increases with $r_{D}$ $φ_{S V} \approx r_{D} / r_{D} + c$	∼ Stable with $r_{D}$ $φ_{S V} \approx 1 - \sqrt{ϵ}$

When the dependence to the parameters is given for the overall rate of rescue $ω,$ it applies to both the rate of rescue from de novo mutations $ω_{D N}$ and from pre-existing variance $ω_{S V} .$ (1) derived from the approximate expression $g (α) \approx α^{- 3 / 2} e^{- α} / (2 \sqrt{π}) .$

Orr and Unckless 2008, 2014; Martin et al. 2013

Table 2. Main results of “context-independent” modelsa and the present model (FGM) when stress only affects rD (only shifts the optimum position in our model).

Table 2. Main results of “context-independent” models^a and the present model (FGM) when stress only affects $r_{D}$ (only shifts the optimum position in our model).