Table 1.

Current anti-PD1 and anti-PD-L1 antitumor therapy.

Antibody	Other names	Brand name	Type	Brand
PD-1 antibodies
Nivolumab	BMS-936558, MDX-1106, ONO-4538	Opdivo	Fully human IgG4 mAb against PD-1	Bristol-Myers Squibb
Pembrolizumab	MK-3475 lambrolizumab	Keytruda	Humanized IgG4-kappa mAb against PD-1	Merck
PD-L1 Ab
Atezolizumab	MPDL3280ARG7446RO5541267	Tecentriq	Fully humanized, engineered monoclonal antibody of IgG1 isotype anti PDL-L1	Roche
Avelumab	MSB0010718C	Bavencio	Human IgG1 lambda monoclonal antibody against PD-L1	EMD SeronoPfizer
Durvalumab	MEDI4736	Imfinzi	Engineered human IgG1 monoclonal antibody against PD-L1	AstraZeneca

mAb, monoclonal antibody; PD-1, programmed cell death-1; PD-L1, programmed death ligand-1; PD-L2, programmed death ligand-2.