FIGURE 5.
Administration of polysaccharides blocks uptake of Cryptococcus particles to hemocytes in the G. mellonella larvae model. Larvae were inoculated with 60 μg of blocking sugars 1 h prior to infection for 2 h with 106 C. neoformans H99 (black bars) or C. gattii R265 (white bars). Uptake of yeast of hemocytes was determined under light microscopy. Results are expressed as the mean ± SD of at least three independent experiments. *p < 0.05 (related to PBS control). ns, not significant (p ≥ 0.05).