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. Author manuscript; available in PMC: 2019 Apr 20.
Published in final edited form as: Org Lett. 2018 Mar 28;20(8):2133–2137. doi: 10.1021/acs.orglett.8b00282

Scheme 3. Alkyl Imine Scopea.

Scheme 3

aReaction conditions: imine 2 (0.20 mol) and phenol 1 (0.03 mmol) and flame-dried 4 Å mol. sieves were added to a solution of Cu(OTf)2 (0.020 mmol) and (S)-Ph-Box (0.030 mmol) in 1 mL of DCE and allowed to stir at rt for 72 h unless otherwise noted. b(S)-iPr-Box used instead of (S)-Ph-Box.