Skip to main content
. Author manuscript; available in PMC: 2018 May 7.
Published in final edited form as: ACS Biomater Sci Eng. 2017 Feb 13;3(3):420–430. doi: 10.1021/acsbiomaterials.6b00805

Figure 3.

Figure 3

Transplanted NSCs survive and proliferate 4 weeks post-TBI. Representative images of the region corresponding to the red dotted box surrounding the lesion area in coronal brain sections obtained from (A) NSC only, and (B) CS-GAG-NSC treated animals. Cellular nuclei are represented by DAPI (blue); transplanted NSCs are represented by PKH26GL labeled cells (red); undifferentiated NSC are represented by Sox1 labeling (yellow); proliferating NSCs are represented by Ki67 labeling (green). Merged overlays are presented in the bottom most panel. Significantly greater PKH26GL+ Sox1+ (C), and Ki67+ (D) NSCs were visualized in CS-GAG-NSC treated animals when compared to NSC only treated animals. Statistical significance is represented by ‘*’, which indicates p < 0.05. Scale = 100 μm.