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. 2018 Apr 18;8(1):1–5. doi: 10.4103/2045-9912.229596

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Copyright: © 2018 Medical Gas Research

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Mixed lineage kinase domain like protein (MLKL) protein and mRNA expression in the brain of mice with cerebral ischemia/reperfusion (I/R) injury.

Note: (A) MLKL protein expression in the brain at 3, 6, 12, 24, and 72 h after reperfusion (n = 5 per group). (B) MLKL protein and mRNA expression in the brain at 24 h after reperfusion (n = 3-5 per group). MLKL protein expression increased at 3 h after reperfusion, peaked at 6-24 h and thereafter decreased at 72 h after reperfusion. In addition, the MLKL protein and mRNA expression was comparable between I/R + hydrogen/oxygen (HO) group and I/R + nitrogen/oxygen (NO) group. *P < 0.05, **P < 0.01, ***P < 0.001, vs. sham group; ^#P < 0.05, vs. 3 h group. h: Hour(s).