Skip to main content
. 2018 Apr 23;2018:5346272. doi: 10.1155/2018/5346272

Figure 1.

Figure 1

Effects of MEKT1, rosiglitazone, and pioglitazone on mRNA expression of Pomc in AtT20 cells. (a) Effects of MEKT1, rosiglitazone, and pioglitazone on mRNA expression of Pomc dose-dependently. AtT20 cells were treated with MEKT1, rosiglitazone (Rosi), and pioglitazone (Pio) (1 nM, 10 nM, 100 nM, 1 μM, or 10 μM) or 0.1% DMSO (vehicle control) for 24 hours. ∗P < 0.05 versus control. (b) Effect of MEKT1 on Pomc mRNA expression time dependently. AtT20 cells were treated with 10 μM MEKT1 for 1 hour, 3 hours, 6 hours, 12 hours, or 24 hours. Vehicle control, 0.1% DMSO. Data are expressed as percentages (100%) of control. Each point indicates mean ± SEM (n = 4). ∗∗∗P < 0.001 versus control.