Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
14-3-3 regulates presynaptic short-term plasticity by modulating CaV2.2 channel properties. 14-3-3 binding reduces cumulative inactivation of CaV2.2 channels and sustains Ca2+ influx and neurotransmitter release (a). Inhibition of 14-3-3 accelerates CaV2.2 channel inactivation and enhances short-term synaptic depression (b).
