Figure 7.

Comparison of liver hepcidin regulator expression among different groups.

Notes: (A) Liver expression of hepcidin, BMP-6, SMAD4, and TfR2 were detected by Western blot, and results were analyzed using ImageJ 1.46r software. Relative abundance of the proteins was expressed relative to β-actin. (B) Data are shown as mean ± SEM (n=8); *P<0.05, **P<0.01 (as compared with Normal); ⁺P<0.05, ⁺⁺P<0.01 (as compared with Model); ^#P<0.05, ^##P<0.01 (as compared with DFX + DFO); ^@P<0.05 (as compared with DFO). Normal: Normal control group, DFX: DFX-treated group, DFO: DFO-treated group, DFX + DFO: DFO and DFX cotreated group, Model: Composite model group.

Abbreviations: DFO, deferoxamine; DFX, deferasirox; SEM, standard error of the mean.