Table 1.

Update of DisMod-MR.

DisMod-2	DisMod-MR	DisMod MR 2.0
(i) Parametric assumption with single number  (ii) Needing more flexible model for estimation  (iii) Adjusted covariate variables  (iv) Lack of meta-analysis, Bayesian inference, regression	(i) Bayesian analysis   (a) Flexible model   (b) Markov Chain Monte Carlo for hierarchical model   (c) Availability of uncertainty interval  (ii) Meta-analysis: global, regional fit  (iii) Regression: adjusted age, comorbidity, etc. (iv) UI of “p X RR”  (v) Adjusting the local fit using global fit with cascade	Faster than DisMod-MR of calculation