Figure 1. HULC knockdown enhanced the sensitivity of PC3 and LNCaP cells to irradiation. A, Survival rate was reduced by irradiation. B, HULC was down-regulated by sh-HULC. C, HULC was up-regulated by pEX-HULC. D, Survival rate after irradiation was further reduced by HULC knockdown. E, Survival rate after irradiation was increased by HULC overexpression. Data are reported as means±SD. **P<0.01; ***P<0.001 (t-test). HULC: long non-coding RNA highly upregulated in liver cancer; sh-HULC: pGPU6/GFP/Neo plasmid carrying short-hairpin RNA targeting HULC; sh-NC: pGPU6/GFP/Neo plasmid carrying a non-targeting RNA; pEX-HULC: pEX-2 plasmid carrying full-length HULC.