Figure 1. Acellular Organ Matrix Maintains Structure and Drives Cell Adhesion.

(A) Acellular matrix from adult rat lung shows alveolar barrier integrity, with retention of yellow micro-particles that are injected into the airway.

(B) Mixed neonatal rat pulmonary epithelium that is seeded onto an acellular lung scaffold organizes to form airway structures containing cells expressing clara cell secretary protein (green) as well as keratin5, a basal cell marker (red).