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. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: Eur J Immunol. 2018 Jan 19;48(3):492–497. doi: 10.1002/eji.201747287

Table 1.

B cell phenotype in spleen and bone marrow (NZBxNZW)F1 and (B6xNZB)F1 mice.

	(NZBxNZW)F1		(B6xNZB)F1
Spleen	Tg+	non-Tg	Tg+	non-Tg
B cells, millions	5.8 ± 2.4^*	26.7 ± 7.6	4.2 ± 1.0^*	29.6 ± 5.9
	(8)	(5)	(5)	(4)
Reduction in B cells vs non-Tg	78%		86%
%Tg+ IgMa (of B cells)	84.7 ± 4.3	N/A	68.2 ± 6.6	N/A
	(8)		(5)
% Endogenous IgMb (of B cells)	24.0 ± 10.0^*	83.8 ± 5.3	32.1 ± 3.0^*	88.0 ± 2.7
	(8)	(5)	(5)	(4)
% lambda+, of B cells	3.2 ± 0.9	2.9 ± 0.5	7.8 ± 1.5^*	3.3 ± 0.7
	(8)	(5)	(5)	(4)
Surface Ig MFI (of B cells)^a	0.8 ± 0.1^*	1.0 ± 0.1	0.7 ± 0.1^*	1.0 ± 0.0
	(3)	(3)	(5)	(4)
Bone Marrow

% B cells, of lymphocytes	20.3 ± 5.0^*	36.2 ± 8.4	21.4 ± 5.9^*	37.7 ± 4.6
	(8)	(5)	(5)	(4)
Surface Ig MFI (of B cells)^a	0.4 ± 0.0^*	1.0 ± 0.2	0.3 ± 0.1	1.0 ± 0.1
	(3)	(3)	(2)	(3)

^*

p<0.05 vs non-Tg

^a

MFI = mean fluorescence intensity, IgM+IgD, normalized to concurrently assayed non-Tg cells.