Table 7.

Reasons for change from standard treatment to LCIG or CSAI and reasons to remain in SOC

Reasons for patients who decided to switch	LCIG (N = 53)	CSAI (N = 19)
	N (%)	N (%)
Caregiver was willing and available to assist patient in managing the advanced PD treatment for a long period	36 (68%)	14 (74%)
The patient could no longer tolerate poor quality of life	42 (79%)	16 (84%)
The patient presented significant disabilities, with serious loss of autonomy	45 (86%)	13 (68%)
The caregiver wished to reduce the stress he/she was undergoing	8 (15%)	3 (16%)
The patient and/or caregiver showed interest in advanced treatment options	23 (43%)	9 (47%)
Complexity of conventional treatments/scarce compliance	10 (19%)	3 (16%)

Reasons for patients to remain in standard treatment	SOC (N = 54)
	N (%)
The caregiver was not willing or available to assist patient in managing the advanced PD treatment for a long period	8 (15%)
The patient is afraid of advanced treatments	30 (56%)
The caregiver is worried for the patient	14 (26%)
The patient believes his or her conditions are not debilitating such as to require an advanced therapy	21 (39%)
The caregiver believes that advanced therapies have to be considered in the very late stage of disease	17 (31%)
The physician believes that the patient is unsuitable for an advanced therapy	17 (31%)
SOC patients who were proposed in the past an advanced therapy but they refused for any reason	18 (33%)